Fluorescent-marked protein is a useful asset for the identification of CAR articulation in research and clinical examples by stream cytometry. These proteins are pre-marked fluorescent colors that can identify CAR articulation by one-venture staining with insignificant foundation. Notwithstanding, the advancement of excellent fluorescent-named proteins presents a significant test and there are just couple of items industrially accessible up until this point.
Formation strategy is a significant bottleneck for growing excellent fluorescent-marked proteins. At present, the most generally involved naming strategy in the market is the conventional substance marking approach. It is an extremely simple strategy to name protein with a fluorescent color in a vague way covalently.
In any case, arbitrary adjustment can prompt heterogeneous and may influence the bioactivity of the protein by means of obstructing the protein-dynamic site. Studies demonstrate that the new-age site-explicit marking innovation can append fluorescent colors to explicit protein in site-explicit way. It gives an assurance to the consistency of the fluorescent-marked items and tries not to influence protein movement. This property makes it a valuable weapon for the improvement of great fluorescent-named protein items with high explicitness and awareness.
ACROBiosystems is taking a stab at fostering the elevated requirement recognition reagents to help the advancement of CAR-T cell treatment. Following quite a while of examination and experience by our specialists, we effectively settled the “Star Staining” site-explicit naming stage and fostered a progression of restrictive fluorescent-marked proteins with “Star Standard” quality. “Star Staining” items can be the incredible assets for identifying and observing CAR-T cells in clinical preliminaries.
Utilizing new-age site-explicit naming innovation to keep up with normal bioactivity
- High particularity and awareness confirmed by stream cytometry
- No vague restricting to non-transduced PBMCs
- High cluster to-bunch consistency and consistency.
Item Feature
- Customary Chemical Labeling
- Non-particular arbitrary marking and influence regular design
- May cover the dynamic locales to lessen bioactivity
- Simple to total because of progress the hydrophilicity of proteins
- High variety in clump to-group consistency
New-age Site-explicit Labeling
- The marking occurs at the particular tag and distant from dynamic locales of proteins
- Keep up with normal compliance and adjustment
- Effectively bio-symmetrical innovation
- High clump to-bunch consistency and consistency.
Apoptosis
Apoptosis is a perplexing and dynamic demise, including the initiation, articulation and guideline of a progression of qualities. Whenever apoptosis happens, a progression of apoptotic processes are modified, for example, phosphatidylserines valgus beyond the cell film, mitochondrial layer Δψm changes, caspase initiation, DNA discontinuity, etc. Unusual apoptotic system can make cells let completely go, which is firmly connected with the event and advancement of numerous infections like growths. Exact identification of apoptotic cells is fundamental in the apoptosis study. Elabscience has effectively fostered different apoptosis identification items (Annexin V Detection Kits, TUNEL Assay Kits,etc) in view of the most generally utilized standards.
Apoptosis Detection Kit.
MCE Annexin V-FITC/PI Apoptosis Detection Kit gives a quick and advantageous technique to recognize cell apoptosis and corruption. In typical live cells, Phosphatidylserine (PS) is situated on the cytoplasmic surface of the cell film. Endless supply of apoptosis, PS moves from the internal to the external pamphlet of the film. Annexin V is a 35-36 kDa Ca2+-subordinate phospholipid-restricting protein that has a high liking for PS.
Annexin V (FITC) | ||||
| abx090611-100tests | Abbexa | 100 tests | 510 EUR | |
Annexin V FITC | ||||
| EXB0024 | ExBio | 100 tests | 244.8 EUR | |
Annexin V, FITC Labeled | ||||
| 20030 | AAT Bioquest | 100 tests | 222 EUR | |
Annexin V, FITC Labeled | ||||
| 20030-100tests | AAT Bioquest | 100 tests | 222 EUR | |
Annexin V, FITC conjugate | ||||
| 29001 | Biotium | 0.5ML | 332.4 EUR | |
Annexin V (ANXA5) Antibody (FITC) | ||||
| abx414513-100tests | Abbexa | 100 tests | 610.8 EUR | |
Annexin V (FITC) / PI Apoptosis Detection Kit | ||||
| abx090601-100tests | Abbexa | 100 tests | 552 EUR | |
Annexin V Apoptosis Detection Kit (FITC) | ||||
| 55R-1265 | Fitzgerald | 25 assays | 332.4 EUR | |
Annexin V Apoptosis Detection Kit (FITC) | ||||
| abx290002-100test | Abbexa | 100 test | 644.4 EUR | |
Annexin V Apoptosis Detection Kit (FITC) | ||||
| abx290014-200test | Abbexa | 200 test | 577.2 EUR | |
Annexin V-FITC Reagent | ||||
| 1001-1000 | Biovision | each | 1495.2 EUR | |
Annexin V-FITC Reagent | ||||
| 1001-200 | Biovision | each | 529.2 EUR | |
Annexin V (FITC) / 7-AAD Apoptosis Detection Kit | ||||
| abx090603-100tests | Abbexa | 100 tests | 594 EUR | |
Annexin V / PI Apoptosis Detection Kit (FITC) | ||||
| abx290007-100test | Abbexa | 100 test | 543.6 EUR | |
Annexin V Apoptosis Detection Kit Plus (FITC) | ||||
| 55R-1302 | Fitzgerald | 25 assays | 355.2 EUR | |
Annexin V / 7ADD Apoptosis Detection Kit (FITC) | ||||
| abx290008-100test | Abbexa | 100 test | 543.6 EUR | |
Aposcreen Annexin V Apoptosis Kit : FITC (OKSB00007) | ||||
| OKSB00007 | Aviva Systems Biology | 100 Tests | 615.6 EUR | |
Annexin V Apoptosis Detection Kit : FITC (OKTA00003) | ||||
| OKTA00003 | Aviva Systems Biology | KIT | 380.4 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K101-100 | Biovision | each | 614.4 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K101-25 | Biovision | each | 268.8 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K101-400 | Biovision | each | 1227.6 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K2003-100 | ApexBio | 100 assays | 619.2 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K2003-25 | ApexBio | 25 assays | 285.6 EUR | |
Annexin V-FITC Apoptosis Kit | ||||
| K2003-400 | ApexBio | 400 assays | 1336.8 EUR | |
Annexin V (PE) | ||||
| abx090613-100tests | Abbexa | 100 tests | 644.4 EUR | |
Annexin V PE | ||||
| EXB0027 | ExBio | 100 tests | 244.8 EUR | |
Annexin A2 antibody (FITC) | ||||
| 60R-1336 | Fitzgerald | 100 ug | 392.4 EUR | |
Annexin A5 antibody (FITC) | ||||
| 60R-1514 | Fitzgerald | 100 ug | 392.4 EUR | |
Annexin A5 Antibody (FITC) | ||||
| 20-abx300581 | Abbexa |
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Annexin V (APC) | ||||
| abx090615-100tests | Abbexa | 100 tests | 718.8 EUR | |
Annexin V APC | ||||
| EXB0028 | ExBio | 100 tests | 244.8 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K201-100 | Biovision | each | 601.2 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K201-25 | Biovision | each | 288 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K201-400 | Biovision | each | 1136.4 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K2057-100 | ApexBio | 100 assays | 619.2 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K2057-25 | ApexBio | 25 assays | 301.2 EUR | |
Annexin V-FITC Apoptosis Kit Plus | ||||
| K2057-400 | ApexBio | 400 assays | 1270.8 EUR | |
Annexin V, CF770 | ||||
| 29046 | Biotium | 25ug | 410.4 EUR | |
Annexin V, CF790 | ||||
| 29047 | Biotium | 25ug | 439.2 EUR | |
Annexin V siRNA | ||||
| 20-abx900343 | Abbexa |
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Annexin V siRNA | ||||
| 20-abx907673 | Abbexa |
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Annexin V siRNA | ||||
| 20-abx907674 | Abbexa |
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Annexin V antibody | ||||
| 70R-11770 | Fitzgerald | 100 ug | 632.4 EUR | |
Annexin V antibody | ||||
| 70R-13691 | Fitzgerald | 100 ug | 386.4 EUR | |
Annexin V Antibody | ||||
| 49376-100ul | SAB | 100ul | 399.6 EUR | |
Annexin V Antibody | ||||
| 49376-50ul | SAB | 50ul | 286.8 EUR | |
Annexin V antibody | ||||
| 10R-7939 | Fitzgerald | 100 ug | 516 EUR | |
Annexin V antibody | ||||
| 20R-1522 | Fitzgerald | 100 ug | 781.2 EUR | |
Annexin V Antibody | ||||
| 3357-100 | Biovision | each | 464.4 EUR | |
Annexin V Antibody | ||||
| 3357-30T | Biovision | each | 175.2 EUR | |
Annexin V Antibody | ||||
| DF6580 | Affbiotech | 200ul | 420 EUR | |
Annexin V Antibody | ||||
| F49706-0.08ML | NSJ Bioreagents | 0.08 ml | 140.25 EUR | |
Annexin V Antibody | ||||
| F49706-0.4ML | NSJ Bioreagents | 0.4 ml | 322.15 EUR | |
Annexin V Antibody | ||||
| F49707-0.08ML | NSJ Bioreagents | 0.08 ml | 140.25 EUR | |
Annexin V Antibody | ||||
| F49707-0.4ML | NSJ Bioreagents | 0.4 ml | 322.15 EUR | |
Annexin V antibody | ||||
| PAab09988 | Lifescience Market | 100 ug | 463.2 EUR | |
Annexin V Antibody | ||||
| RQ5261 | NSJ Bioreagents | 100ul | 356.15 EUR | |
Annexin V Antibody | ||||
| R30176 | NSJ Bioreagents | 100 ug | 356.15 EUR | |
Annexin V Antibody | ||||
| R31475 | NSJ Bioreagents | 100 ug | 356.15 EUR | |
Annexin V, sulforhodamine 101 conjugate (Texas-Red Annexin V) | ||||
| 29002 | Biotium | 0.5ML | 332.4 EUR | |
Annexin V, Recombinant | ||||
| 20014 | AAT Bioquest | 100 ug | 222 EUR | |
Annexin V, Recombinant | ||||
| 20015 | AAT Bioquest | 1 mg | 1509 EUR | |
Annexin V, Recombinant | ||||
| 20014-100ug | AAT Bioquest | 100 ug | 222 EUR | |
Annexin V, Recombinant | ||||
| 20015-1mg | AAT Bioquest | 1 mg | 1509 EUR | |
Annexin A1 (ANXA1) Antibody (FITC) | ||||
| 20-abx106557 | Abbexa |
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Annexin A1 (ANXA1) Antibody (FITC) | ||||
| 20-abx106558 | Abbexa |
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Annexin A1 (ANXA1) Antibody (FITC) | ||||
| 20-abx106559 | Abbexa |
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Annexin A2 (ANXA2) Antibody (FITC) | ||||
| 20-abx106560 | Abbexa |
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Annexin A3 (ANXA3) Antibody (FITC) | ||||
| 20-abx106562 | Abbexa |
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Annexin A5 (ANXA5) Antibody (FITC) | ||||
| 20-abx106563 | Abbexa |
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Annexin V named with green fluorescent FITC can recognize apoptotic cells by restricting to PS uncovered on the external flyer. Propidium Iodide (PI) is a cell-film impermeable color to live cells and early apoptosis cells, yet stains late apoptosis cells and corruption cells with red fluorescence. In the wake of staining, live cells show practically no fluorescence (Annexin V-/PI-), early apoptosis cells show green fluorescence (Annexin V+/PI-), late apoptosis cells and corruption cells show red and green fluorescence (Annexin V+/PI+).